PT-141 (Bremelanotide)

Description

PT-141 Overview

PT-141, also known as Bremelanotide, is a synthetic peptide analog of α-melanocyte-stimulating hormone (α-MSH).

It is studied in laboratory and preclinical models for its ability to activate the melanocortin receptors MC3R and MC4R, which are involved in neuroendocrine signaling, energy regulation and vascular pathways. It belongs to the same melanocortin research family as Melanotan II.

PT-141 Research Focus

Published laboratory and preclinical work on this peptide has concentrated on the following areas:

• MC3R and MC4R activation
• Neuroendocrine signaling
• Energy regulation pathways
• Vascular pathways

Available Formats

PT-141 is available in 10mg vials. Each strength can be ordered as a single vial or as a pack of 10 vials; choose your options above before adding to the cart.

Handling and Storage

Store and handle this product according to the product label and your laboratory’s standard operating procedures. For background on the factors that affect stability, such as temperature, moisture, light and repeated freeze-thaw cycles, read our guide to peptide storage and stability.

Where PT-141 Fits in Our Range

Melanocortin peptides are analogs of α-melanocyte-stimulating hormone (α-MSH) studied for their activity at melanocortin receptors. This category includes the linear analog Melanotan I, the cyclic analog Melanotan II and PT-141 (Bremelanotide), studied at MC3R and MC4R.

Choosing a Format

The strength printed on a vial describes the total amount of material it contains, not a concentration. Work out how much material each planned experiment uses before ordering. The 10-vial pack suits a longer series of experiments, while a single vial suits a pilot run.

General Laboratory Handling

These are general principles for handling lyophilized peptides. The label and your own procedures take priority over them.

• Lyophilized peptides are generally far more stable than peptides in solution, so keep material dry until it is needed.
• Store sealed vials cold and away from light and moisture.
• Let a cold vial reach room temperature before opening it, so that condensation does not form on the powder.
• Divide reconstituted material into single-use aliquots to avoid repeated freeze-thaw cycles.
• Record the lot number, the date opened and the diluent used.

Checking Identity and Purity

Identity, purity and peptide content are separate questions. Mass spectrometry is typically used to confirm molecular mass, reversed-phase HPLC to assess purity, and amino acid analysis to measure peptide content. Our overview of analytical techniques in peptide research explains how these methods work and what each result can and cannot show.

Reference

Dorr R.T. et al. (1996). Find this reference on PubMed.

PT-141 FAQs

What is PT-141?

PT-141, also known as Bremelanotide, is a synthetic peptide analog of α-melanocyte-stimulating hormone (α-MSH).

What has this peptide been studied for?

Published work has concentrated on MC3R and MC4R activation and neuroendocrine signaling. See the research focus section above for the full list.

Which strengths are available?

10mg, each sold as a single vial or as a pack of 10 vials.

Can this product be used in people or animals?

No. It is sold only for laboratory research, and we cannot give dosing or human-use guidance.

Where can I ask a question about this product?

Use our contact page, or email support@directpeptiides.com. Include your order number if your question is about an order.

Related Research Peptides

• Melanotan II: Melanotan II (MT-II) is a synthetic cyclic heptapeptide analog of α-MSH.
• Melanotan I: Melanotan I is a synthetic 13-amino-acid analog of alpha-MSH, modified at two positions to resist enzymatic breakdown.
• Kisspeptin: Kisspeptin is a central signaling peptide of the hypothalamic-pituitary-gonadal (HPG) axis that acts through KISS1R.

Browse the full Melanocortin Peptides range or search the shop.