Sermorelin

Description

Sermorelin Overview

Sermorelin is a synthetic peptide analog of GHRH (1-29), corresponding to the first 29 amino acids of growth hormone-releasing hormone.

It is studied in laboratory and preclinical models for its ability to modulate somatotroph axis signaling and, through that, downstream cascades and associated pathway activity. Research has focused on its role in endocrine modulation, molecular dynamics and structural remodeling processes.

Sermorelin Research Focus

Published laboratory and preclinical work on this peptide has concentrated on the following areas:

• Somatotroph axis signaling
• Endocrine modulation
• Molecular dynamics
• Structural remodeling processes

Available Formats

Sermorelin is available in 5mg vials. Each strength can be ordered as a single vial or as a pack of 10 vials; choose your options above before adding to the cart.

Handling and Storage

Store and handle this product according to the product label and your laboratory’s standard operating procedures. For background on the factors that affect stability, such as temperature, moisture, light and repeated freeze-thaw cycles, read our guide to peptide storage and stability.

Where Sermorelin Fits in Our Range

This category brings together peptides studied for their effects on the somatotroph (growth hormone) axis. It includes GHRH analogs such as Sermorelin, Tesamorelin, CJC-1295 No DAC and CJC-1295 with DAC, secretagogue-type peptides such as Ipamorelin and Hexarelin, and the IGF-1 analog IGF-1 LR3.

Choosing a Format

The strength printed on a vial describes the total amount of material it contains, not a concentration. Work out how much material each planned experiment uses before ordering. The 10-vial pack suits a longer series of experiments, while a single vial suits a pilot run.

General Laboratory Handling

These are general principles for handling lyophilized peptides. The label and your own procedures take priority over them.

• Lyophilized peptides are generally far more stable than peptides in solution, so keep material dry until it is needed.
• Store sealed vials cold and away from light and moisture.
• Let a cold vial reach room temperature before opening it, so that condensation does not form on the powder.
• Divide reconstituted material into single-use aliquots to avoid repeated freeze-thaw cycles.
• Record the lot number, the date opened and the diluent used.

Checking Identity and Purity

Identity, purity and peptide content are separate questions. Mass spectrometry is typically used to confirm molecular mass, reversed-phase HPLC to assess purity, and amino acid analysis to measure peptide content. Our overview of analytical techniques in peptide research explains how these methods work and what each result can and cannot show.

Reference

Walker R.F. et al. (1994). Find this reference on PubMed.

Sermorelin FAQs

What is Sermorelin?

Sermorelin is a synthetic peptide analog of GHRH (1-29), corresponding to the first 29 amino acids of growth hormone-releasing hormone.

What has this peptide been studied for?

Published work has concentrated on Somatotroph axis signaling and endocrine modulation. See the research focus section above for the full list.

Which strengths are available?

5mg, each sold as a single vial or as a pack of 10 vials.

Can this product be used in people or animals?

No. It is sold only for laboratory research, and we cannot give dosing or human-use guidance.

Where can I ask a question about this product?

Use our contact page, or email support@directpeptiides.com. Include your order number if your question is about an order.

Related Research Peptides

• Tesamorelin: Tesamorelin is a synthetic GHRH analog designed to modulate somatotroph axis signaling in experimental research.
• CJC-1295 No DAC: CJC-1295 No DAC is a modified GHRH(1-29) analog with four amino acid substitutions that resist DPP-4 degradation.
• Ipamorelin: Ipamorelin is a synthetic pentapeptide and selective secretagogue-type agonist studied for its selective pituitary signaling.

Browse the full Growth Hormone Axis Peptides range or search the shop.