VIP (Vasoactive Intestinal Peptide)

Description

VIP Overview

Vasoactive intestinal peptide (VIP) is a neuropeptide made up of 28 amino acids. It was originally isolated from intestinal tissue and belongs to the glucagon/secretin superfamily of signaling peptides.

Since its discovery in 1970, VIP has been studied extensively in controlled experimental settings. Research has examined its potential influence on smooth muscle relaxation, receptor signaling and immune regulation.

VIP Research Focus

Published laboratory and preclinical work on this peptide has concentrated on the following areas:

• Smooth muscle relaxation in experimental models
• Receptor signaling within the glucagon/secretin family
• Immune regulation
• Neuropeptide signaling

Available Formats

VIP is available in 10mg vials. Each strength can be ordered as a single vial or as a pack of 10 vials; choose your options above before adding to the cart.

Handling and Storage

Store and handle this product according to the product label and your laboratory’s standard operating procedures. For background on the factors that affect stability, such as temperature, moisture, light and repeated freeze-thaw cycles, read our guide to peptide storage and stability.

Where VIP Fits in Our Range

This category covers peptides studied in neuronal, neuroendocrine and behavioral signaling research. It includes the heptapeptides Selank and Semax, DSIP, Oxytocin, the HPG axis regulator Kisspeptin and VIP (vasoactive intestinal peptide).

Choosing a Format

The strength printed on a vial describes the total amount of material it contains, not a concentration. Work out how much material each planned experiment uses before ordering. The 10-vial pack suits a longer series of experiments, while a single vial suits a pilot run.

General Laboratory Handling

These are general principles for handling lyophilized peptides. The label and your own procedures take priority over them.

• Lyophilized peptides are generally far more stable than peptides in solution, so keep material dry until it is needed.
• Store sealed vials cold and away from light and moisture.
• Let a cold vial reach room temperature before opening it, so that condensation does not form on the powder.
• Divide reconstituted material into single-use aliquots to avoid repeated freeze-thaw cycles.
• Record the lot number, the date opened and the diluent used.

Checking Identity and Purity

Identity, purity and peptide content are separate questions. Mass spectrometry is typically used to confirm molecular mass, reversed-phase HPLC to assess purity, and amino acid analysis to measure peptide content. Our overview of analytical techniques in peptide research explains how these methods work and what each result can and cannot show.

Reference

Said S.I., Mutt V. (1970). Find this reference on PubMed.

VIP FAQs

What is VIP?

Vasoactive intestinal peptide (VIP) is a neuropeptide made up of 28 amino acids.

What has this peptide been studied for?

Published work has concentrated on Smooth muscle relaxation in experimental models and receptor signaling within the glucagon/secretin family. See the research focus section above for the full list.

Which strengths are available?

10mg, each sold as a single vial or as a pack of 10 vials.

Can this product be used in people or animals?

No. It is sold only for laboratory research, and we cannot give dosing or human-use guidance.

Where can I ask a question about this product?

Use our contact page, or email support@directpeptiides.com. Include your order number if your question is about an order.

Related Research Peptides

• Oxytocin: Oxytocin is a cyclic nonapeptide with a disulfide bridge between cysteines at positions 1 and 6.
• Thymosin Alpha 1: Thymosin Alpha 1 (Tα1) is a naturally occurring 28-amino-acid peptide originally isolated from thymic tissue.
• Selank: Selank is a synthetic heptapeptide analog of tuftsin, a natural immunomodulatory fragment of IgG.

Browse the full Neuropeptides & Neuroendocrine range or search the shop.