DSIP

Description

DSIP Overview

DSIP is a small amphiphilic peptide made up of nine amino acids (Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu). It has shown effects on circadian signaling and neuroendocrine regulation in experimental models.

It was first identified through its ability to modulate delta-wave patterns in experimental systems. Since then it has been studied for its influence on circadian rhythms, EEG patterns and hypothalamic-pituitary-adrenal (HPA) axis activity, with research also pointing to effects on GABAergic and serotonergic signaling, corticosterone and ACTH dynamics, and oxidative stress responses.

DSIP Research Focus

Published laboratory and preclinical work on this peptide has concentrated on the following areas:

• Circadian rhythm signaling
• Delta-wave and EEG patterns
• HPA axis activity
• GABAergic and serotonergic signaling

Available Formats

DSIP is available in 10mg vials. Each strength can be ordered as a single vial or as a pack of 10 vials; choose your options above before adding to the cart.

Handling and Storage

Store and handle this product according to the product label and your laboratory’s standard operating procedures. For background on the factors that affect stability, such as temperature, moisture, light and repeated freeze-thaw cycles, read our guide to peptide storage and stability.

Where DSIP Fits in Our Range

This category covers peptides studied in neuronal, neuroendocrine and behavioral signaling research. It includes the heptapeptides Selank and Semax, DSIP, Oxytocin, the HPG axis regulator Kisspeptin and VIP (vasoactive intestinal peptide).

Choosing a Format

The strength printed on a vial describes the total amount of material it contains, not a concentration. Work out how much material each planned experiment uses before ordering. The 10-vial pack suits a longer series of experiments, while a single vial suits a pilot run.

General Laboratory Handling

These are general principles for handling lyophilized peptides. The label and your own procedures take priority over them.

• Lyophilized peptides are generally far more stable than peptides in solution, so keep material dry until it is needed.
• Store sealed vials cold and away from light and moisture.
• Let a cold vial reach room temperature before opening it, so that condensation does not form on the powder.
• Divide reconstituted material into single-use aliquots to avoid repeated freeze-thaw cycles.
• Record the lot number, the date opened and the diluent used.

Checking Identity and Purity

Identity, purity and peptide content are separate questions. Mass spectrometry is typically used to confirm molecular mass, reversed-phase HPLC to assess purity, and amino acid analysis to measure peptide content. Our overview of analytical techniques in peptide research explains how these methods work and what each result can and cannot show.

Reference

Schoenenberger et al. (1977). Find this reference on PubMed.

DSIP FAQs

What is DSIP?

DSIP is a small amphiphilic peptide made up of nine amino acids (Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu).

What has this peptide been studied for?

Published work has concentrated on Circadian rhythm signaling and delta-wave and EEG patterns. See the research focus section above for the full list.

Which strengths are available?

10mg, each sold as a single vial or as a pack of 10 vials.

Can this product be used in people or animals?

No. It is sold only for laboratory research, and we cannot give dosing or human-use guidance.

Where can I ask a question about this product?

Use our contact page, or email support@directpeptiides.com. Include your order number if your question is about an order.

Related Research Peptides

• Selank: Selank is a synthetic heptapeptide analog of tuftsin, a natural immunomodulatory fragment of IgG.
• Semax: Semax is a synthetic heptapeptide derived from ACTH (4-10) with an added C-terminal Pro-Gly-Pro sequence.
• Kisspeptin: Kisspeptin is a central signaling peptide of the hypothalamic-pituitary-gonadal (HPG) axis that acts through KISS1R.

Browse the full Neuropeptides & Neuroendocrine range or search the shop.